Scientific Achievement
- Researchers in the Soft Matter Electron Microscopy program discovered that 3D peptoid crystals can be obtained by modifying terminus
Significance and Impact
- Oligopeptoids usually form 2D crystals due to the dominance of preferred growth axes, but many applications from energy conversion to drug delivery require 3D crystals
Research Details
- 4D-STEM imaging revealed relationship between chemical structure crystalline motif
- More compact terminal groups lead to higher degree of perfection in 3D crystals
Publication Details
Y.J. Lee, P. Ercius, X. Luo, G.L. Butterfoss, T. Yu, J. Zhang, D. Prendergast, A.M. Minor, N.P. Balsara, R.N. Zuckermann, B.A. Abel, X. Jiang. Nano Letters (2025).
DOI: 10.1021/acs.nanolett.5c02506
Work was performed in the Molecular Foundry and NERSC.
